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Anti-LCK Monoclonal Antibody
Cat: K000071M
Summary:
【Product name】:Anti-LCK Monoclonal Antibody 【Source】:Mouse
【Isotype】:IgG1 【Purification】:Affinity purification
【Gene ID】:3932 【Swiss Prot】:P06239
【Tested applications】:WB
【Recommended dilution】:WB 1:500-1000.
【Immunogen】:Recombinant protein of human LCK
【Storage】:Store at -20℃. Avoid freeze / thaw cycles.
Background:
This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein is a key signaling molecule in the selection and maturation of developing T-cells. It contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to the plasma membrane and pericentrosomal vesicles, and binds to cell surface receptors, including CD4 and CD8, and other signaling molecules. Multiple alternatively spliced variants, encoding the same protein, have been described.
Verified picture:
Western blot analysis with LCK antibody diluted at 1:1000;Lane: Ramos Jurkat.