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Anti-RAD9A Monoclonal Antibody
Cat: K000094M
Summary:
【Product name】:Anti-RAD9A Monoclonal Antibody 【Source】:Mouse
【Isotype】:IgG2b 【Purification】:Affinity purification
【Gene ID】:5883 【Swiss Prot】:Q99638
【Tested applications】:IP,WB
【Recommended dilution】:WB 1:500-1000. IP 1:20.
【Immunogen】:Recombinant protein of human RAD9A
【Storage】:Store at -20℃. Avoid freeze / thaw cycles.
Background:
This gene product is highly similar to Schizosaccharomyces pombe rad9,a cell cycle checkpoint protein required for cell cycle arrest and DNA damage repair.This protein possesses 3' to 5' exonuclease activity,which may contribute to its role in sensing and repairing DNA damage.It forms a checkpoint protein complex with RAD1 and HUS1.This complex is recruited by checkpoint protein RAD17 to the sites of DNA damage,which is thought to be important for triggering the checkpoint-signaling cascade.Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq,Aug 2011]
Verified picture:
Western blot analysis with RAD9A antibody diluted at 1:1000;Lane: Rat testis MCF-7 COS7 HeLa 3T3.