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Anti-TNFRSF10B Monoclonalal Antibody
Cat: K000102M
Summary:
【Product name】:Anti-TNFRSF10B Monoclonalal Antibody 【Source】:Mouse
【Isotype】:IgG1 【Purification】:Affinity purification
【Gene ID】:8795 【Swiss Prot】:O14763
【Tested applications】:IF,ICC,WB
【Recommended dilution】:WB 1:500-1000. IF 1:50-200. ICC 1:50-200.
【Immunogen】:Recombinant protein of human TNFRSF10B
【Storage】:Store at -20℃. Avoid freeze / thaw cycles.
Background:
The protein encoded by this gene is a member of the TNF-receptor superfamily,and contains an intracellular death domain.This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand(TNFSF10/TRAIL/APO-2L),and transduces an apoptosis signal.Studies with FADD-deficient mice suggested that FADD,a death domain containing adaptor protein,is required for the apoptosis mediated by this protein.Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene.[provided by RefSeq,Mar 2009]
Verified picture:
Western blot analysis with TNFRSF10B antibody diluted at 1:1000;Lane: Mouse kindey Mouse brain HCT116 HeLa.
Immunofluorescence analysis of HeLa using TNFRSF10B antibody diluted at 1:100.