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Anti-PCNA Monoclonal Antibody - RBITC
Cat: K000119M - RBITC
Summary:
【Product name】:Anti-PCNA Monoclonal Antibody - RBITC 【Source】:Mouse
【Isotype】:IgG2b 【Purification】:Fractional precipitation
【Gene ID】:5111 【Swiss Prot】:P12004
【Tested applications】:WB ELISA IHC ICC IF
【Recommended dilution】:ICC 1:50-200. IF 1:50-200
【Immunogen】:Recombinant protein of human PCNA
【Storage】:Store at -20℃. Avoid freeze / thaw cycles.
Background:
The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta.The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication.In response to DNA damage,this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway.Two transcript variants encoding the same protein have been found for this gene.Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome.[provided by RefSeq,Jul 2008]
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