Anti-SMARCA4 Monoclonal Antibody
Cat: K000144M
Summary:
| 【Product name】：Anti-SMARCA4 Monoclonal Antibody | 【Source】：Mouse |
| 【Isotype】：IgG1 | 【Purification】：Affinity purification |
| 【Gene ID】：6597 | 【Swiss Prot】：P51532 |
| 【Tested applications】：ICC,IP,IF,WB | |
| 【Recommended dilution】：WB 1:500-1000. IF 1:50-200. IP 1:20. ICC 1:50-200. | |
| 【Immunogen】：Recombinant protein of human SMARCA4 | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
The protein encoded by this gene is a member of the SWI/SNF family of proteins and is similar to the brahma protein of Drosophila.Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes.The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI,which is required for transcriptional activation of genes normally repressed by chromatin.In addition, this protein can bind BRCA1,as well as regulate the expression of the tumorigenic protein CD44.Mutations in this gene cause rhabdoid tumor predisposition syndrome type 2.Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq,May 2012]
Verified picture:
Western blot analysis with SMARCA4 antibody diluted at 1:1000;Lane: K562 F9 HeLa.
Immunofluorescence analysis of HeLa using SMARCA4 antibody diluted at 1:100.
Immunoprecipitation analysis of K562 extracts using SMARCA4 antibody(IP:1:20;WB:1:1000).Control IgG: Normal Mouse IgG.