Anti-SIRT1 Monoclonal Antibody
Cat: K000147M
Summary:
| 【Product name】：Anti-SIRT1 Monoclonal Antibody | 【Source】：Mouse |
| 【Isotype】：IgG2b | 【Purification】：Affinity purification |
| 【Gene ID】：23411 | 【Swiss Prot】：Q96EB6 |
| 【Tested applications】：IP,WB | |
| 【Recommended dilution】：WB 1:500-1000. IP 1:20. | |
| 【Immunogen】：Recombinant protein of human SIRT1 | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
This gene encodes a member of the sirtuin family of proteins,homologs to the yeast Sir2 protein.Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes.The functions of human sirtuins have not yet been determined;however,yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA.Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity.The protein encoded by this gene is included in class I of the sirtuin family.Alternative splicing results in multiple transcript variants.[provided by RefSeq,Dec 2008]
Verified picture:
Western blot analysis with SIRT1 antibody diluted at 1:1000;Lane: CEM A549 Ramos Jurkat HeLa.
Immunoprecipitation analysis of HeLa extracts using SIRT1 antibody(IP:1:20;WB:1:1000).Control IgG: Normal Mouse IgG.