Anti-XRCC1 Monoclonal Antibody
Cat: K000148M
Summary:
| 【Product name】：Anti-XRCC1 Monoclonal Antibody | 【Source】：Mouse |
| 【Isotype】：IgG1 | 【Purification】：Affinity purification |
| 【Gene ID】：7515 | 【Swiss Prot】：P18887 |
| 【Tested applications】：WB | |
| 【Recommended dilution】：WB 1:500-1000. | |
| 【Immunogen】：Recombinant protein of human XRCC1 | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
The protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents.This protein interacts with DNA ligase III,polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway.It may play a role in DNA processing during meiogenesis and recombination in germ cells.A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.[provided by RefSeq,Jul 2008]
Verified picture:
Western blot analysis with XRCC1 antibody diluted at 1:1000;Lane: Raji K562 HeLa Jurkat THP-1.