Anti-ATG7 Polyclonal Antibody
Cat: K000331P
Summary:
| 【Product name】：Anti-ATG7 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：10533 | 【Swiss Prot】：O95352 |
| 【Tested applications】：IHC,IF | |
| 【Recommended dilution】：IHC 1:50-200. IF 1:50-200. | |
| 【Immunogen】：Recombinant protein of human ATG7 | |
| 【Public Immunogen Range】：500-676aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
This gene encodes an E1-like activating enzyme that is essential for autophagy and cytoplasmic to vacuole transport. The encoded protein is also thought to modulate p53-dependent cell cycle pathways during prolonged metabolic stress. It has been associated with multiple functions, including axon membrane trafficking, axonal homeostasis, mitophagy, adipose differentiation, and hematopoietic stem cell maintenance. Alternative splicing results in multiple transcript variants.
Verified picture:
Immunohistochemistry of paraffin-embedded human colon carcinoma with ATG7 antibody diluted at 1:100.
Immunofluorescence analysis of A549 cells using ATG7 antibody diluted at 1:100.