Anti-YAP1 Polyclonal Antibody
Cat: K000333P
Summary:
| 【Product name】：Anti-YAP1 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：10413 | 【Swiss Prot】：P46937 |
| 【Tested applications】：IF,IHC,WB | |
| 【Recommended dilution】：WB 1:500-1000. IHC 1:50-100. IF 1:50-200. | |
| 【Immunogen】：Recombinant protein of human YAP1 | |
| 【Public Immunogen Range】：155-504aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms.
Verified picture:
Immunohistochemistry of paraffin-embedded human stomach using YAP1 antibody at dilution of 1:100 (x40 lens).
Western blot analysis with YAP1 antibody diluted at 1:1000;Lane: DU145 BT-474.
Immunohistochemistry of paraffin-embedded human liver cancer with YAP1 antibody diluted at 1:75.
Immunofluorescence analysis of C6 cells using YAP1 antibody diluted at 1:100.