Anti-PDX1 Polyclonal Antibody
Cat: K000335P
Summary:
| 【Product name】：Anti-PDX1 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：3651 | 【Swiss Prot】：P52945 |
| 【Tested applications】：WB | |
| 【Recommended dilution】：WB 1:500-1000 | |
| 【Immunogen】：A synthetic peptide of human PDX1 | |
| 【Public Immunogen Range】：1-100aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
The protein encoded by this gene is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. The encoded nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in this gene are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM), as well as maturity onset diabetes of the young type 4 (MODY4).
Verified picture:
Western blot analysis with PDX1 antibody diluted at 1:700;Lane: DU145 HepG2 Mouse pancreas Mouse liver.