Anti-TARDBP Polyclonal Antibody
Cat: K000341P
Summary:
| 【Product name】：Anti-TARDBP Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：23435 | 【Swiss Prot】：Q13148 |
| 【Tested applications】：RIP,IP,WB | |
| 【Recommended dilution】：WB 1:500-2000. IP 0.5μg-4μg. RIP 1:20-50. | |
| 【Immunogen】：Recombinant protein of human TARDBP | |
| 【Public Immunogen Range】：1-260aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20.
Verified picture:
Western blot analysis with TARDBP antibody diluted at 1:1000;Lane: HeLa Jurkat SW620 HT-29 A-673 Es-2 Mouse spleen.