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Anti-HNRNPK Polyclonal Antibody
Cat: K000355P
Summary:
【Product name】:Anti-HNRNPK Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:3190 【Swiss Prot】:P61978
【Tested applications】:WB,IF,IHC
【Recommended dilution】:WB 1:500-2000. IHC 1:50-200. IF 1:50-200.
【Immunogen】:Recombinant protein of human HNRNPK
【Public Immunogen Range】:1-280aa
【Storage】:Store at -20℃. Avoid freeze/thaw cycles.
Background:
This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene is located in the nucleoplasm and has three repeats of KH domains that binds to RNAs. It is distinct among other hnRNP proteins in its binding preference; it binds tenaciously to poly(C). This protein is also thought to have a role during cell cycle progession. Several alternatively spliced transcript variants have been described for this gene, however, not all of them are fully characterized.
Verified picture:
Immunohistochemistry of paraffin-embedded Breast cancer(hu) using HNRNPK antibody at dilution of 1:100(x100 lens x200 lens).
Immunofluorescence analysis of MCF7 cell using HNRNPK antibody. Blue: DAPI for nuclear staining.
Immunofluorescence analysis of A549 cell using HNRNPK antibody.
Western blot analysis with HNRNPK antibody diluted at 1:1000;Lane: HeLa Jurkat 293T MCF7 HepG2 PC-12 Mouse testis.
Immunohistochemistry of paraffin-embedded rat liver with HNRNPK antibody diluted at 1:100.