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Anti-ATG4A Polyclonal Antibody
Cat: K000371P
Summary:
【Product name】:Anti-ATG4A Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:115201 【Swiss Prot】:Q8WYN0
【Tested applications】:WB,IF
【Recommended dilution】:WB 1:100-500. IF 1:50-200.
【Immunogen】:Recombinant protein of human ATG4A
【Public Immunogen Range】:210-398aa
【Storage】:Store at -20℃. Avoid freeze/thaw cycles.
Background:
Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases.
Verified picture:
Immunohistochemistry of paraffin-embedded breast cancer(hu) using ATG4A antibody at dilution of 1:100(x100 lens x200 lens).
Western blot analysis with ATG4A antibody diluted at 1:1000;Lane: HeLa Mouse liver Rat lung.
Immunofluorescence analysis of NIH3T3 cells using ATG4A antibody diluted at 1:100.