Anti-BACE1 Polyclonal Antibody
Cat: K000384P
Summary:
| 【Product name】：Anti-BACE1 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：23621 | 【Swiss Prot】：P56817 |
| 【Tested applications】：WB,IF,IHC | |
| 【Recommended dilution】：WB 1:100-500. IHC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：Recombinant protein of human BACE1 | |
| 【Public Immunogen Range】：22-322aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
This gene encodes a member of the peptidase A1 family of aspartic proteases. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protease. This transmembrane protease catalyzes the first step in the formation of amyloid beta peptide from amyloid precursor protein. Amyloid beta peptides are the main constituent of amyloid beta plaques, which accumulate in the brains of human Alzheimer's disease patients.
Verified picture:
Western blot analysis with BACE1 antibody diluted at 1:500;Lane: SH-SY5Y.
Immunohistochemistry of paraffin-embedded mouse hippocampus using BACE1 antibody diluted at 1:20.
Immunofluorescence analysis of SH-SY5Y cells using BACE1 antibody diluted at 1:100.