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Anti-TIA1 Polyclonal Antibody
Cat: K000425P
Summary:
【Product name】:Anti-TIA1 Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:7072 【Swiss Prot】:P31483
【Tested applications】:WB,IF,IHC
【Recommended dilution】:WB 1:500-2000. IHC 1:50-200. IF 1:20-100.
【Immunogen】:Recombinant protein of human TIA1
【Storage】:Store at -20℃. Avoid freeze/thaw cycles.
Background:
The product encoded by this gene is a member of a RNA-binding protein family and possesses nucleolytic activity against cytotoxic lymphocyte (CTL) target cells. It has been suggested that this protein may be involved in the induction of apoptosis as it preferentially recognizes poly(A) homopolymers and induces DNA fragmentation in CTL targets. The major granule-associated species is a 15-kDa protein that is thought to be derived from the carboxyl terminus of the 40-kDa product by proteolytic processing. Alternative splicing resulting in different isoforms of this gene product has been described in the literature.
Verified picture:
Immunohistochemistry of paraffin-embedded human lung cancer tissue using TIA1 antibody at dilution of 1:100 (x40 lens).
Immunofluorescence analysis of HeLa cell using TIA1 antibody. Blue: DAPI for nuclear staining.
Western blot analysis with TIA1 antibody diluted at 1:1000;Lane: BT-474.
Immunohistochemistry of paraffin-embedded rat brain with TIA1 antibody diluted at 1:100.