Anti-TBL1XR1 Monoclonal Antibody
Cat: K001366M
Summary:
| 【Product name】：Anti-TBL1XR1 Monoclonal Antibody | 【Source】：Mouse |
| 【Isotype】：IgG1 | 【Purification】：Affinity purification |
| 【Gene ID】：79718 | 【Swiss Prot】：Q9BZK7 |
| 【Tested applications】：IF,ICC,IHC,WB | |
| 【Recommended dilution】：WB 1:500-1000. IHC 1:50-100. IF 1:50-200. ICC 1:50-200. | |
| 【Immunogen】：Recombinant protein of human TBL1XR1 | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
TBLR1 is an F-box-like protein involved in the recruitment of the ubiquitin/19S proteasome complex to nuclear receptor-regulated transcription units. It plays an essential role in transcription activation mediated by nuclear receptors and probably acts as an integral component of the N-Cor corepressor complex that mediates the recruitment of the 19S proteasome complex, leading to the subsequent proteosomal degradation of the N-Cor complex, thereby allowing cofactor exchange, and transcription activation.
Verified picture:
Western blot analysis with TBL1XR1 antibody diluted at 1:1000;Lane: Mouse brain Mouse heart K562.
Immunohistochemistry of paraffin-embedded Human breast cancer with TBLR1 antibody diluted at 1:500-1000
Immunofluorescence analysis of HeLa using TBL1XR1 antibody diluted at 1:100.