下载
Anti-PPP1CA Monoclonal Antibody
Cat: K001380M
Summary:
【Product name】:Anti-PPP1CA Monoclonal Antibody 【Source】:Mouse
【Isotype】:IgG1 【Purification】:Affinity purification
【Gene ID】:5499 【Swiss Prot】:P62136
【Tested applications】:IF,ICC,WB
【Recommended dilution】:WB 1:500-1000. IF 1:50-200. ICC 1:50-200.
【Immunogen】:Recombinant protein of human PPP1CA
【Storage】:Store at -20℃. Avoid freeze / thaw cycles.
Background:
The protein encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Increased PP1 activity has been observed in the end stage of heart failure. Studies in both human and mice suggest that PP1 is an important regulator of cardiac function. Mouse studies also suggest that PP1 functions as a suppressor of learning and memory. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Verified picture:
Western blot analysis with PPP1CA antibody diluted at 1:1000;Lane: HepG2 MCF-7 HeLa.
Immunofluorescence analysis of HeLa using PPP1CA antibody diluted at 1:100.