下载
Anti-STAT1 Monoclonal Antibody
Cat: K001439M
Summary:
【Product name】:Anti-STAT1 Monoclonal Antibody 【Source】:Mouse
【Isotype】:IgG2a 【Purification】:Affinity purification
【Gene ID】:6772 【Swiss Prot】:P42224
【Tested applications】:IP,WB
【Recommended dilution】:WB 1:500-1000. IP 1:20.
【Immunogen】:Recombinant protein of human STAT1
【Storage】:Store at -20℃. Avoid freeze / thaw cycles.
Background:
The protein encoded by this gene is a member of the STAT protein family.In response to cytokines and growth factors,STAT family members are phosphorylated by the receptor associated kinases,and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators.This protein can be activated by various ligands including interferon-alpha,interferon-gamma,EGF,PDGF and IL6.This protein mediates the expression of a variety of genes,which is thought to be important for cell viability in response to different cell stimuli and pathogens.Two alternatively spliced transcript variants encoding distinct isoforms have been described.[provided by RefSeq,Jul 2008]
Verified picture:
Western blot analysis with STAT1 antibody diluted at 1:1000;Lane: SW480 MCF7 A549 COS7 HeLa.
Immunoprecipitation analysis of HeLa extracts using STAT1 antibody(IP:1:20;WB:1:1000).Control IgG: Normal Mouse IgG.