Anti-HDAC1 Polyclonal Antibody
Cat: K001617P
Summary:
| 【Product name】：Anti-HDAC1 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：3065 | 【Swiss Prot】：Q13547 |
| 【Tested applications】：WB,IF,IHC,IP | |
| 【Recommended dilution】：WB 1:500-1000. IHC 1:50-200. IF 1:50-100. IP 0.5μg-4μg. | |
| 【Immunogen】：A synthetic peptide of human HDAC1 | |
| 【Public Immunogen Range】：393-482aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis.
Verified picture:
Immunohistochemistry of paraffin-embedded breast cancer��hu��using HDAC1 antibody at dilution of 1:100 (x100 lens��x200 lens).
Immunofluorescence analysis of A549 cell using HDAC1 antibody. Blue: DAPI for nuclear staining.
Immunoprecipitation analysis of 200ug extracts of HT-29 cells, using 3 ug HDAC1 antibody.
Western blot analysis with HDAC1 antibody diluted at 1:1000;Lane: 293T HeLa HepG2 MCF7 Mouse thymus Mouse testis Rat thymus Rat testis.
Immunohistochemistry of paraffin-embedded rat spleen with HDAC1 antibody diluted at 1:150.