Anti-IGF1R Polyclonal Antibody - SAlexa Fluor 405
Cat: K001621P - SAlexa Fluor 405
Summary:
| 【Product name】：Anti-IGF1R Polyclonal Antibody - SAlexa Fluor 405 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：3480 | 【Swiss Prot】：P08069 |
| 【Tested applications】：WB | |
| 【Recommended dilution】：WB 1:1000-5000. | |
| 【Immunogen】：Recombinant protein of human IGF1R | |
| 【Public Immunogen Range】：1201-1367aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
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