Anti-IKBKE Polyclonal Antibody
Cat: K001622P
Summary:
| 【Product name】：Anti-IKBKE Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：9641 | 【Swiss Prot】：Q14164 |
| 【Tested applications】：IF,IHC,WB | |
| 【Recommended dilution】：WB 1:500-2000. IHC 1:50-200. IF 1:50-200. | |
| 【Immunogen】：Recombinant protein of human IKBKE | |
| 【Public Immunogen Range】：497-716aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
IKBKE is a noncanonical I-kappa-B (see MIM 164008) kinase (IKK) that is essential for regulating antiviral signaling pathways. IKBKE has also been identified as a breast cancer (MIM 114480) oncogene and is amplified and overexpressed in over 30% of breast carcinomas and breast cancer cell lines (Hutti et al., 2009 [PubMed 19481526]).
Verified picture:
Immunohistochemistry of paraffin-embedded pancreatic cancer(hu) using IKBKE antibody at dilution of 1:100 (x100 lens��x200 lens).
Western blot analysis with IKBKE antibody diluted at 1:1000;Lane: SW480 DU145 MCF7 Mouse liver.
Immunohistochemistry of paraffin-embedded human colon carcinoma with IKBKE antibody diluted at 1:100.