Anti-MCL1 Polyclonal Antibody
Cat: K001628P
Summary:
| 【Product name】：Anti-MCL1 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：4170 | 【Swiss Prot】：Q07820 |
| 【Tested applications】：WB,IHC,IF | |
| 【Recommended dilution】：WB 1:500-2000. IHC 1:50-200. IF 1:50-200. | |
| 【Immunogen】：A synthetic peptide of human MCL1 | |
| 【Public Immunogen Range】：150-250aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
This gene encodes an anti-apoptotic protein, which is a member of the Bcl-2 family. Alternative splicing results in multiple transcript variants. The longest gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene products (isoform 2 and isoform 3) promote apoptosis and are death-inducing.
Verified picture:
Immunohistochemistry of paraffin-embedded mouse brain using MCL1 antibody at dilution of 1:100 (x40 lens).
Western blot analysis with MCL1 antibody diluted at 1:1000;Lane: BT-474 Raji Mouse lung Mouse thymus.
Immunofluorescence analysis of NIH3T3 cells using MCL1 antibody diluted at 1:100.