Anti-NME1 Polyclonal Antibody - SAlexa Fluor 568
Cat: K001637P - SAlexa Fluor 568
Summary:
| 【Product name】：Anti-NME1 Polyclonal Antibody - SAlexa Fluor 568 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：4830 | 【Swiss Prot】：P15531 |
| 【Tested applications】：WB,IHC | |
| 【Recommended dilution】：WB 1:500-1000. IHC 1:50-200. | |
| 【Immunogen】：A synthetic peptide of human NME1 | |
| 【Public Immunogen Range】：77-177aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
This gene (NME1) was identified because of its reduced mRNA transcript levels in highly metastatic cells. Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of 'A' (encoded by this gene) and 'B' (encoded by NME2) isoforms. Mutations in this gene have been identified in aggressive neuroblastomas. Two transcript variants encoding different isoforms have been found for this gene. Co-transcription of this gene and the neighboring downstream gene (NME2) generates naturally-occurring transcripts (NME1-NME2), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product.
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