Anti-ApoE Polyclonal Antibody
Cat: K001672P
Summary:
| 【Product name】：Anti-ApoE Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：348 | 【Swiss Prot】：P02649 |
| 【Tested applications】：WB,IF,IHC | |
| 【Recommended dilution】：WB 1:100-500. IHC 1:50-200. IF 1:50-200. | |
| 【Immunogen】：Recombinant protein of human ApoE | |
| 【Public Immunogen Range】：41-307aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
The protein encoded by this gene is a major apoprotein of the chylomicron. It binds to a specific liver and peripheral cell receptor, and is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. This gene maps to chromosome 19 in a cluster with the related apolipoprotein C1 and C2 genes. Mutations in this gene result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants.
Verified picture:
Immunohistochemistry of paraffin-embedded mouse lung using ApoE antibody at dilution of 1:100 (x40 lens).
Western blot analysis with ApoE antibody diluted at 1:1000;Lane: SH-SY5Y.
Immunohistochemistry of paraffin-embedded human placenta with ApoE antibody diluted at 1:100.
Immunofluorescence analysis of HepG2 cells using ApoE antibody diluted at 1:100.