Anti-FASN Polyclonal Antibody
Cat: K001685P
Summary:
| 【Product name】：Anti-FASN Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：2194 | 【Swiss Prot】：P49327 |
| 【Tested applications】：IF,IHC,WB | |
| 【Recommended dilution】：WB 1:500-1000. IHC 1:50-200. IF 1:50-200. | |
| 【Immunogen】：Recombinant protein of human FASN | |
| 【Public Immunogen Range】：2221-2511aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
The enzyme encoded by this gene is a multifunctional protein. Its main function is to catalyze the synthesis of palmitate from acetyl-CoA and malonyl-CoA, in the presence of NADPH, into long-chain saturated fatty acids. In some cancer cell lines, this protein has been found to be fused with estrogen receptor-alpha (ER-alpha), in which the N-terminus of FAS is fused in-frame with the C-terminus of ER-alpha.
Verified picture:
Immunohistochemistry of paraffin-embedded mouse liver using FASN antibody at dilution of 1:100 (x40 lens).
Immunofluorescence analysis of A549 cell using FASN antibody. Blue: DAPI for nuclear staining.
Western blot analysis with FASN antibody diluted at 1:1000;Lane: MCF7 A549 Mouse liver Mouse thymus Rat liver.
Immunohistochemistry of paraffin-embedded human breast cancer with FASN antibody diluted at 1:100.
Immunofluorescence analysis of C6 cells using FASN antibody diluted at 1:100.