Anti-MYCN Polyclonal Antibody
Cat: K001690P
Summary:
| 【Product name】：Anti-MYCN Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：4613 | 【Swiss Prot】：P04198 |
| 【Tested applications】：WB,IHC,IF | |
| 【Recommended dilution】：WB 1:100-500. IHC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：Recombinant protein of human MYCN | |
| 【Public Immunogen Range】：168-267aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
This gene is a member of the MYC family and encodes a protein with a basic helix-loop-helix (bHLH) domain. This protein is located in the nucleus and must dimerize with another bHLH protein in order to bind DNA. Amplification of this gene is associated with a variety of tumors, most notably neuroblastomas. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Verified picture:
Immunohistochemistry of paraffin-embedded mouse brain with MYCN antibody diluted at 1:100.
Western blot analysis with MYCN antibody diluted at 1:500;Lane: HeLa.
Immunofluorescence analysis of rat brain using MYCN antibody diluted at 1:50.