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Anti-CRKL Polyclonal Antibody
Cat: K001692P
Summary:
【Product name】:Anti-CRKL Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:1399 【Swiss Prot】:P46109
【Tested applications】:WB
【Recommended dilution】:WB 1:500-2000.
【Immunogen】:A synthetic peptide of human CRKL
【Public Immunogen Range】:201-300aa
【Storage】:Store at -20℃. Avoid freeze/thaw cycles.
Background:
This gene encodes a protein kinase containing SH2 and SH3 (src homology) domains which has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion. It is a substrate of the BCR-ABL tyrosine kinase, plays a role in fibroblast transformation by BCR-ABL, and may be oncogenic.
Verified picture:
Western blot analysis with CRKL antibody diluted at 1:1000;Lane: MCF7 HeLa Raji Mouse brain Mouse thymus Mouse liver.