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Anti-NEDD4 Polyclonal Antibody - Cy3
Cat: K001700P - Cy3
Summary:
【Product name】:Anti-NEDD4 Polyclonal Antibody - Cy3 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:4734 【Swiss Prot】:P46934
【Tested applications】:ICC IF
【Recommended dilution】:ICC 1:50-200. IF 1:50-200
【Immunogen】:Recombinant protein of human NEDD4
【Public Immunogen Range】:160-460aa
【Storage】:Store at -20℃. Avoid freeze/thaw cycles.
Background:
This gene is the founding member of the NEDD4 family of HECT ubiquitin ligases that function in the ubiquitin proteasome system of protein degradation. The encoded protein contains an N-terminal calcium and phospholipid binding C2 domain followed by multiple tryptophan-rich WW domains and, a C-terminal HECT ubiquitin ligase catalytic domain. It plays critical role in the regulation of a number of membrane receptors, endocytic machinery components and the tumor suppressor PTEN.
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