Anti-EZR Polyclonal Antibody
Cat: K001735P
Summary:
| 【Product name】：Anti-EZR Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：7430 | 【Swiss Prot】：P15311 |
| 【Tested applications】：WB,IF,IP | |
| 【Recommended dilution】：WB 1:500-2000. IF 1:50-100. IP 0.5μg-4μg. | |
| 【Immunogen】：Recombinant protein of human EZR | |
| 【Public Immunogen Range】：350-470aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers. A pseudogene located on chromosome 3 has been identified for this gene. Alternatively spliced variants have also been described for this gene.
Verified picture:
Western blot analysis with EZR antibody diluted at 1:1000;Lane: M21 SW480 U-251MG 293T Mouse intestine Mouse brain Rat brain.
Immunofluorescence analysis of C6 cells using EZR antibody diluted at 1:100.