Anti-XRCC6 Polyclonal Antibody
Cat: K001756P
Summary:
| 【Product name】：Anti-XRCC6 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：2547 | 【Swiss Prot】：P12956 |
| 【Tested applications】：WB,IHC,IF | |
| 【Recommended dilution】：WB 1:500-2000. IHC 1:50-200. IF 1:50-200. | |
| 【Immunogen】：A synthetic peptide of human XRCC6 | |
| 【Public Immunogen Range】：408-609aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus.
Verified picture:
Immunohistochemistry of paraffin-embedded stomach cancer(hu) using XRCC6 antibody (A0842) at dilution of 1:100 (x100 lens��x200 lens).
Immunofluorescence analysis of HeLa cells using XRCC6 antibody (A0883) at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.
Western blot analysis with XRCC6 antibody diluted at 1:1000;Lane: SKOV3 COS7 SW480 HeLa Mouse brain Mouse liver Mouse skeletal muscle Rat liver.
Immunohistochemistry of paraffin-embedded rat brain with XRCC6 antibody diluted at 1:100.
Immunofluorescence analysis of U2OS cells using XRCC6 antibody diluted at 1:100.