Anti-XRCC6 Polyclonal Antibody - RBITC
Cat: K001756P - RBITC
Summary:
| 【Product name】：Anti-XRCC6 Polyclonal Antibody - RBITC | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：2547 | 【Swiss Prot】：P12956 |
| 【Tested applications】：WB ELISA IHC ICC IF | |
| 【Recommended dilution】：ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：A synthetic peptide of human XRCC6 | |
| 【Public Immunogen Range】：408-609aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus.
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