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Anti-XRCC6 Polyclonal Antibody - SAlexa Fluor 532
Cat: K001756P - SAlexa Fluor 532
Summary:
【Product name】:Anti-XRCC6 Polyclonal Antibody - SAlexa Fluor 532 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:2547 【Swiss Prot】:P12956
【Tested applications】:WB,IHC,IF
【Recommended dilution】:WB 1:500-2000. IHC 1:50-200. IF 1:50-200.
【Immunogen】:A synthetic peptide of human XRCC6
【Public Immunogen Range】:408-609aa
【Storage】:Store at -20℃. Avoid freeze/thaw cycles.
Background:
The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus.
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