Anti-MARCKS Polyclonal Antibody
Cat: K001765P
Summary:
| 【Product name】：Anti-MARCKS Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：4082 | 【Swiss Prot】：P29966 |
| 【Tested applications】：WB,IF | |
| 【Recommended dilution】：WB 1:500-2000. IHC 1:50-200. | |
| 【Immunogen】：A synthetic peptide of human MARCKS | |
| 【Public Immunogen Range】：1-100aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
The protein encoded by this gene is a substrate for protein kinase C. It is localized to the plasma membrane and is an actin filament crosslinking protein. Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with actin and with the plasma membrane, leading to its presence in the cytoplasm. The protein is thought to be involved in cell motility, phagocytosis, membrane trafficking and mitogenesis.
Verified picture:
Immunohistochemistry of paraffin-embedded esophageal cancer��hu�� using MARCKS antibody at dilution of 1:100 (x100 lens��x200 lens).
Western blot analysis with MARCKS antibody diluted at 1:1000;Lane: Rat brain.
Immunofluorescence analysis of C6 cells using MARCKS antibody diluted at 1:100.