Anti-TGM2 Polyclonal Antibody
Cat: K001786P
Summary:
| 【Product name】：Anti-TGM2 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：7052 | 【Swiss Prot】：P21980 |
| 【Tested applications】：WB,IHC,IF | |
| 【Recommended dilution】：WB 1:500-1000. IHC 1:50-200. IF 1:50-200. | |
| 【Immunogen】：Recombinant protein of human TGM2 | |
| 【Public Immunogen Range】：299-548aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. Finally, the encoded protein is the autoantigen implicated in celiac disease. Two transcript variants encoding different isoforms have been found for this gene.
Verified picture:
Immunohistochemistry of paraffin-embedded human stomach using TGM2 antibody.
Western blot analysis with TGM2 antibody diluted at 1:1000;Lane: A549 K-562.
Immunohistochemistry of paraffin-embedded human colon carcinoma with TGM2 antibody diluted at 1:150.
Immunofluorescence analysis of NIH3T3 cells using TGM2 antibody diluted at 1:100.