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Anti-IL17RA Polyclonal Antibody - SAlexa Fluor 633
Cat: K001826P - SAlexa Fluor 633
Summary:
【Product name】:Anti-IL17RA Polyclonal Antibody - SAlexa Fluor 633 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:23765 【Swiss Prot】:Q96F46
【Tested applications】:WB
【Recommended dilution】:WB 1:1000-4000
【Immunogen】:Recombinant protein of human IL17RA
【Public Immunogen Range】:33-320aa
【Storage】:Store at -20℃. Avoid freeze/thaw cycles.
Background:
Interleukin 17A (IL17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The transmembrane protein encoded by this gene (interleukin 17A receptor; IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure. Alternative splicing results in multiple transcript variants encoding different isoforms.
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