Anti-SCN1B Polyclonal Antibody - SAlexa Fluor 405
Cat: K001833P - SAlexa Fluor 405
Summary:
| 【Product name】：Anti-SCN1B Polyclonal Antibody - SAlexa Fluor 405 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：6324 | 【Swiss Prot】：Q07699 |
| 【Tested applications】：WB | |
| 【Recommended dilution】：WB 1:500-2000. | |
| 【Immunogen】：Recombinant protein of human SCN1B | |
| 【Public Immunogen Range】：19-160aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Voltage-gated sodium channels are heteromeric proteins that function in the generation and propagation of action potentials in muscle and neuronal cells. They are composed of one alpha and two beta subunits, where the alpha subunit provides channel activity and the beta-1 subunit modulates the kinetics of channel inactivation. This gene encodes a sodium channel beta-1 subunit. Mutations in this gene result in generalized epilepsy with febrile seizures plus, Brugada syndrome 5, and defects in cardiac conduction. Multiple transcript variants encoding different isoforms have been found for this gene.
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