Anti-DAG1 Polyclonal Antibody
Cat: K001835P
Summary:
| 【Product name】：Anti-DAG1 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：1605 | 【Swiss Prot】：Q14118 |
| 【Tested applications】：WB,IF,IP | |
| 【Recommended dilution】：WB 1:1000-5000. IF 1:20-100. IP 0.5μg-4μg. | |
| 【Immunogen】：Recombinant protein of human DAG1 | |
| 【Public Immunogen Range】：776-895aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
This gene encodes dystroglycan, a central component of dystrophin-glycoprotein complex that links the extracellular matrix and the cytoskeleton in the skeletal muscle. The encoded preproprotein undergoes O- and N-glycosylation, and proteolytic processing to generate alpha and beta subunits. Certain mutations in this gene are known to cause distinct forms of muscular dystrophy. Alternative splicing results in multiple transcript variants, all encoding the same protein.
Verified picture:
Immunohistochemistry of paraffin-embedded Colorectal cancer(hu) using DAG1 antibody at dilution of 1:100 (x100 lens��x200 lens).
Western blot analysis with DAG1 antibody diluted at 1:700;Lane: HepG2 U2OS SW480 HeLa mouse skeletal muscle mouse lung mouse heart rat liver rat lung.