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Anti-CD53 Polyclonal Antibody
Cat: K001837P
Summary:
【Product name】:Anti-CD53 Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:963 【Swiss Prot】:P19397
【Tested applications】:WB
【Recommended dilution】:WB 1:1000-4000
【Immunogen】:Recombinant protein of human CD53
【Public Immunogen Range】:100-180aa
【Storage】:Store at -20℃. Avoid freeze/thaw cycles.
Background:
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. It contributes to the transduction of CD2-generated signals in T cells and natural killer cells and has been suggested to play a role in growth regulation. Familial deficiency of this gene has been linked to an immunodeficiency associated with recurrent infectious diseases caused by bacteria, fungi and viruses. Alternative splicing results in multiple transcript variants.
Verified picture:
Immunohistochemistry of paraffin-embedded Esophageal cancer(hu) using CD53 antibody at dilution of 1:100 (x100 lens��x200 lens).
Western blot analysis with CD53 antibody diluted at 1:3000;Lane: B cells Jurkat Raji HL-60 Mouse liver Mouse spleen Mouse lung.