Anti-PCDH15 Polyclonal Antibody - SAlexa Fluor 405
Cat: K001840P - SAlexa Fluor 405
Summary:
| 【Product name】：Anti-PCDH15 Polyclonal Antibody - SAlexa Fluor 405 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：65217 | 【Swiss Prot】：Q96QU1 |
| 【Tested applications】：WB,IHC | |
| 【Recommended dilution】：WB 1:500-2000.IHC 1:100-200 | |
| 【Immunogen】：Recombinant protein of human PCDH15 | |
| 【Public Immunogen Range】：160-400aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
This gene is a member of the cadherin superfamily. Family members encode integral membrane proteins that mediate calcium-dependent cell-cell adhesion. It plays an essential role in maintenance of normal retinal and cochlear function. Mutations in this gene result in hearing loss and Usher Syndrome Type IF (USH1F). Extensive alternative splicing resulting in multiple isoforms has been observed in the mouse ortholog. Similar alternatively spliced transcripts are inferred to occur in human, and additional variants are likely to occur.
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