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Anti-IARS Polyclonal Antibody
Cat: K001875P
Summary:
【Product name】:Anti-IARS Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:3376 【Swiss Prot】:P41252
【Tested applications】:WB
【Recommended dilution】:WB 1:500-2000.
【Immunogen】:Recombinant protein of human IARS
【Public Immunogen Range】:1158-1262aa
【Storage】:Store at -20℃. Avoid freeze/thaw cycles.
Background:
Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAS, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Isoleucine-tRNA synthetase belongs to the class-I aminoacyl-tRNA synthetase family and has been identified as a target of autoantibodies in the autoimmune disease polymyositis/dermatomyositis. Alternatively spliced transcript variants have been found.
Verified picture:
Immunohistochemistry of paraffin-embedded Breast cancer(hu) using IARS antibody at dilution of 1:100 (x100 lens��x200 lens).
Western blot analysis with IARS antibody diluted at 1:1000;Lane: HeLa HepG2 HT-29 HL-60 Jurkat.