Anti-KRT8 Polyclonal Antibody
Cat: K001899P
Summary:
| 【Product name】：Anti-KRT8 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：3856 | 【Swiss Prot】：P05787 |
| 【Tested applications】：IHC,WB,IF | |
| 【Recommended dilution】：WB 1:2000-4000. IHC 1:50-200. IF 1:50-200. | |
| 【Immunogen】：Recombinant protein of human KRT8 | |
| 【Public Immunogen Range】：1-483aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene.
Verified picture:
Western blot analysis with KRT8 antibody diluted at 1:1000;Lane: HeLa Jurkat.
Immunohistochemistry of paraffin-embedded colorectal cancer��hu�� using KRT8 antibody at dilution of 1:100 (x100 lens��x200 lens).
Immunofluorescence analysis of A549 cell using KRT8 antibody. Blue: DAPI for nuclear staining.
Immunohistochemistry of paraffin-embedded human colon carcinoma with KRT8 antibody diluted at 1:100.
Immunofluorescence analysis of HeLa cells using KRT8 antibody diluted at 1:100.