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Anti-INVS Polyclonal Antibody - SAlexa Fluor 488
Cat: K001930P - SAlexa Fluor 488
Summary:
【Product name】:Anti-INVS Polyclonal Antibody - SAlexa Fluor 488 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:27130 【Swiss Prot】:Q9Y283
【Tested applications】:FC ICC IF
【Recommended dilution】:Flow-Cyt 1:50-200. ICC 1:50-200. IF 1:50-200
【Immunogen】:Recombinant protein of human INVS
【Public Immunogen Range】:1-90aa
【Storage】:Store at -20℃. Avoid freeze/thaw cycles.
Background:
This gene encodes a protein containing multiple ankyrin domains and two IQ calmodulin-binding domains. The encoded protein may function in renal tubular development and function, and in left-right axis determination. This protein interacts with nephrocystin and infers a connection between primary cilia function and left-right axis determination. A similar protein in mice interacts with calmodulin. Mutations in this gene have been associated with nephronophthisis type 2. Multiple transcript variants encoding distinct isoforms have been identified for this gene.
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