Anti-CHMP2A Polyclonal Antibody - SAlexa Fluor 555
Cat: K001968P - SAlexa Fluor 555
Summary:
| 【Product name】：Anti-CHMP2A Polyclonal Antibody - SAlexa Fluor 555 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：27243 | 【Swiss Prot】：O43633 |
| 【Tested applications】：ICC IF | |
| 【Recommended dilution】：ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：Recombinant protein of human CHMP2A | |
| 【Public Immunogen Range】：1-222aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
CHMP2A belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006 [PubMed 16730941]).
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