Anti-LMAN1 Polyclonal Antibody
Cat: K001998P
Summary:
| 【Product name】：Anti-LMAN1 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：3998 | 【Swiss Prot】：P49257 |
| 【Tested applications】：IF,IHC,WB | |
| 【Recommended dilution】：WB 1:500-2000.IHC 1:50-100.IF 1:50-200 | |
| 【Immunogen】：Recombinant protein of human LMAN1 | |
| 【Public Immunogen Range】：270-480aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
The protein encoded by this gene is a membrane mannose-specific lectin that cycles between the endoplasmic reticulum, endoplasmic reticulum-Golgi intermediate compartment, and cis-Golgi, functioning as a cargo receptor for glycoprotein transport. The protein has an N-terminal signal sequence, a calcium-dependent and pH-sensitive carbohydrate recognition domain, a stalk region that functions in oligomerization, a transmembrane domain, and a short cytoplasmic domain required for organelle targeting. Allelic variants of this gene are associated with the autosomal recessive disorder combined factor V-factor VIII deficiency.
Verified picture:
Western blot analysis with LMAN1 antibody diluted at 1:1000;Lane: BT-474 LO2 U-251MG.
Immunofluorescence analysis of C6 cells using LMAN1 antibody diluted at 1:100.