Anti-PDE1A Polyclonal Antibody
Cat: K002006P
Summary:
| 【Product name】：Anti-PDE1A Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：5136 | 【Swiss Prot】：P54750 |
| 【Tested applications】：WB | |
| 【Recommended dilution】：WB 1:500-2000. | |
| 【Immunogen】：Recombinant protein of human PDE1A | |
| 【Public Immunogen Range】：446-545aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Cyclic nucleotide phosphodiesterases (PDEs) play a role in signal transduction by regulating intracellular cyclic nucleotide concentrations through hydrolysis of cAMP and/or cGMP to their respective nucleoside 5-prime monophosphates. Members of the PDE1 family, such as PDE1A, are Ca(2+)/calmodulin (see CALM1; MIM 114180)-dependent PDEs (CaM-PDEs) that are activated by calmodulin in the presence of Ca(2+) (Michibata et al., 2001 [PubMed 11342109]; Fidock et al., 2002 [PubMed 11747989]).
Verified picture:
Immunohistochemistry of paraffin-embedded Colorectal cancer��hu) using PDE1A antibody at dilution of 1:100 (100x lens).
Western blot analysis with PDE1A antibody diluted at 1:1000;Lane: Mouse heart Mouse brain Mouse kidney Rat heart Rat brain.