Anti-NFKBIZ Polyclonal Antibody - SAlexa Fluor 555
Cat: K002023P - SAlexa Fluor 555
Summary:
| 【Product name】：Anti-NFKBIZ Polyclonal Antibody - SAlexa Fluor 555 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：64332 | 【Swiss Prot】：Q9BYH8 |
| 【Tested applications】：ICC IF | |
| 【Recommended dilution】：ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：Recombinant protein of human NFKBIZ | |
| 【Public Immunogen Range】：1-220aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
This gene is a member of the ankyrin-repeat family and is induced by lipopolysaccharide (LPS). The C-terminal portion of the encoded product which contains the ankyrin repeats, shares high sequence similarity with the I kappa B family of proteins. The latter are known to play a role in inflammatory responses to LPS by their interaction with NF-B proteins through ankyrin-repeat domains. Studies in mouse indicate that this gene product is one of the nuclear I kappa B proteins and an activator of IL-6 production. Two transcript variants encoding different isoforms have been found for this gene.
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