Anti-P2RX7 Polyclonal Antibody - SAlexa Fluor 680
Cat: K002032P - SAlexa Fluor 680
Summary:
| 【Product name】：Anti-P2RX7 Polyclonal Antibody - SAlexa Fluor 680 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：5027 | 【Swiss Prot】：Q99572 |
| 【Tested applications】：WB | |
| 【Recommended dilution】：WB 1:500-1000. | |
| 【Immunogen】：Recombinant protein of human P2RX7 | |
| 【Public Immunogen Range】：47-334aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Activation of this nuclear receptor by ATP in the cytoplasm may be a mechanism by which cellular activity can be coupled to changes in gene expression. Multiple alternatively spliced variants have been identified, most of which fit nonsense-mediated decay (NMD) criteria.
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