Anti-P2RX7 Polyclonal Antibody - Cy5
Cat: K002032P - Cy5
Summary:
| 【Product name】：Anti-P2RX7 Polyclonal Antibody - Cy5 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：5027 | 【Swiss Prot】：Q99572 |
| 【Tested applications】：FC ICC IF | |
| 【Recommended dilution】：Flow-Cyt 1:50-200. ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：Recombinant protein of human P2RX7 | |
| 【Public Immunogen Range】：47-334aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Activation of this nuclear receptor by ATP in the cytoplasm may be a mechanism by which cellular activity can be coupled to changes in gene expression. Multiple alternatively spliced variants have been identified, most of which fit nonsense-mediated decay (NMD) criteria.
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