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Anti-RHOC Polyclonal Antibody - SAlexa Fluor 532
Cat: K002067P - SAlexa Fluor 532
Summary:
【Product name】:Anti-RHOC Polyclonal Antibody - SAlexa Fluor 532 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:389 【Swiss Prot】:P08134
【Tested applications】:WB
【Recommended dilution】:WB 1:500-1000.
【Immunogen】:Recombinant protein of human RHOC
【Public Immunogen Range】:1-193aa
【Storage】:Store at -20℃. Avoid freeze/thaw cycles.
Background:
This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The protein encoded by this gene is prenylated at its C-terminus, and localizes to the cytoplasm and plasma membrane. It is thought to be important in cell locomotion. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified.
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