Anti-PDIA3 Polyclonal Antibody
Cat: K002098P
Summary:
| 【Product name】：Anti-PDIA3 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：2923 | 【Swiss Prot】：P30101 |
| 【Tested applications】：WB,IF,IHC | |
| 【Recommended dilution】：WB 1:500-2000.IHC 1:50-100.IF 1:50-100 | |
| 【Immunogen】：Recombinant protein of human PDIA3 | |
| 【Public Immunogen Range】：206-505aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
This gene encodes a protein of the endoplasmic reticulum that interacts with lectin chaperones calreticulin and calnexin to modulate folding of newly synthesized glycoproteins. The protein was once thought to be a phospholipase; however, it has been demonstrated that the protein actually has protein disulfide isomerase activity. It is thought that complexes of lectins and this protein mediate protein folding by promoting formation of disulfide bonds in their glycoprotein substrates. This protein also functions as a molecular chaperone that prevents the formation of protein aggregates.
Verified picture:
Immunohistochemistry of paraffin-embedded colorectal cancer��hu�� using PDIA3 antibody at dilution of 1:100 (x100 lens��x200 lens).
Western blot analysis with PDIA3 antibody diluted at 1:1000;Lane: NIH3T3 MCF7 Jurkat HepG2 LO2 Mouse brain Mouse thymus Mouse liver Rat liver.
Immunohistochemistry of paraffin-embedded human stomach with PDIA3 antibody diluted at 1:75.